HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 6-AMINO-1-BENZYL-5-BROMOURACIL
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 6-Amino-1-benzyluracil | HCID 250746 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-AMINO-1-BENZYL-5-BROMOURACIL | HCID 822149 | — |
Reaction Steps
A solution of bromine (33.17 ml) in acetic acid (300 ml) was added slowly to a solution of 6-amino-1-benzyluracil and anhydrous sodium acetate (93.29 g) in acetic acid (300 ml) and stirred for 6 hours. The reaction mixture was cooled in ice-cold water. The precipitate was filtered and dried under vacuum to provide 6-amino-1-benzyl-5-bromouracil (134.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06774130B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-6e60c33df26d4ed98f27d48becedd096 |
| Source note | uspto-grants-2004_08 |