反应详情

To a solution of the product of Example 11 in methylene chloride at 0° C. is added carbon tetrabromide and triphenylphosphine. The reaction is stirred for 2 hours and the solvent is removed under reduced pressure. The crude product is dissolved in an eluting solvent system and chromatographed to afford the title compound.

1. customthe solvent is removed under reduced pressure
2. dissolutionThe crude product is dissolved in an eluting solvent system
3. customchromatographed