Acetonitrile → HCID 9794302, compound

HRID 1835761Notes

Reaction equation

[C:1](Cl)(=[O:5])[C:2](Cl)=[O:3].[N:7]1([CH:15]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[CH2:14]CCCCCN1.C(#[N:25])C>>[CH2:22]([CH:15]1[N:7]2[C:1](=[O:5])[C:2](=[O:3])[N:25]=[C:14]2[CH2:17][CH2:16]1)[CH2:21][CH2:20][CH2:19][CH3:18]

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 65578Oxalyl chloride

HCID 66583054Diazabicyclooctane

Product 1

HCID 9794302HCID 9794302, compound

Procedure

Ex-31) The product of Example 31d is treated with oxalyl chloride and diazabicyclooctane in acetonitrile to give the title compound, which is purified by partition between water and EtOAc, and passage over a silica column.

Sources & evidence

ORD record: ord-fd493871318a4aef879b17114d7642a3
Source dataset: uspto-grants-2004_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06774126B2

Reaction notes

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