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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836124Generated: October 26, 2026

Dimethylamine → 3-[3-(4-Methylpiperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde

https://huagongshe.com/reaction/1836124

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant1-MethylpiperazineHCID 53167—
Reactant3-(3-(Dimethylamino)propyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehydeHCID 11230063—
Product3-[3-(4-Methylpiperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehydeHCID 22571132—

Reaction Steps

3-[3-(4-Methylpiperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde was prepared following the procedure described for 3-(3-dimethylamino-propyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde as described for Example 1 above but substituting 1-methylpiperazine in step 2 above for dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777417B2
Source datasetuspto-grants-2004_08
ORD IDord-96b86d98d2fb4b09b14db05bffafc9e5
Source noteuspto-grants-2004_08