HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23498840, compound → HCID 44299266, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23498840 | HCID 23498840 | — |
| Reactant | HCID 23498854 | HCID 23498854 | — |
| Product | HCID 44299266 | HCID 44299266 | 65% |
Reaction Steps
3-[3-(4-Acetyl-piperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (70 mg, 0.22 mmol), prepared as described in Example 10 above, was condensed with 5-ethylsulfonyloxindole (69.5 mg, 1.01 eq, 72% pure) following the procedure used in Example 1 above. The formed solid was purified by flash chromatography using (dichloromethane: methanol 50/1, 30/1) to give 75 mg of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777417B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-29c596c0333f41c58379894e848cae72 |
| Source note | uspto-grants-2004_08 |