反应详情

3-[3-(4-Formyl-piperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (91 mg, 0.3 mmol), prepared as described in Example 8, Steps 1-4 above, was condensed with 5-ethylsulfonyloxindole (67 mg, 0.3 mmol, 50%pure) following the procedure used in Example 1 above. The reaction mixture was purified by flash chromatography using (dichloromethane: methanol 30/1, 20/1, 15/1) to give (100 mg, 64% yield) of the desired product.

1. customThe reaction mixture was purified by flash chromatography