HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23498814, compound → HCID 60104769, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23498814 | HCID 23498814 | — |
| Reactant | HCID 23498854 | HCID 23498854 | — |
| Product | HCID 60104769 | HCID 60104769 | 65.3% |
Reaction Steps
3-[3-(4-Formyl-piperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (91 mg, 0.3 mmol), prepared as described in Example 8, Steps 1-4 above, was condensed with 5-ethylsulfonyloxindole (67 mg, 0.3 mmol, 50%pure) following the procedure used in Example 1 above. The reaction mixture was purified by flash chromatography using (dichloromethane: methanol 30/1, 20/1, 15/1) to give (100 mg, 64% yield) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777417B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-39f2a10b5bb54981987535344c9c41e5 |
| Source note | uspto-grants-2004_08 |