反应详情

3-[3-(4-Hydroxy-piperidin-1-yl)-3-oxo-propyl]-1,5,6,7-tetrahydro-indol-4-one was prepared by following the procedure described for the synthesis of 4-[3-(4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl)-propionyl]-piperazine-1-carboxylic acid tert-butyl ester (Step 1 of example 8) by substituting tert-butyl 1-piperazinecarboxylate with piperidin-4-ol.