Ammonia → HCID 10448521, compound

Participants

Reaction Steps

Aqueous concentrated ammonia (150 ml) was added to a stirred suspension of 3-(4-acetoxybutyl)-6-(3-ethyl-4-methylanilino)uracil (10.5 g, 24 mmol) in 150 ml of methanol at room temperature. After 30 minutes, all solid was dissolved, and the solution was stirred for 72 hours. The solvent was removed, and the solid was co-evaporated three times with methanol, and filtered from methanol to give the product as a white solid (9.0 g, 97%).

Provenance & Evidence