Methyl iodide → HCID 12727037, compound

HRID 1836350Notes

Reaction equation

HRID 1836350 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[C:6]([C:8]1[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=1)=[O:7].[I:17][CH3:18]>CC(C)=O>[I-:17].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[C:6]([C:8]1[CH:13]=[CH:12][N+:11]([CH3:18])=[CH:10][CH:9]=1)=[O:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 23499332HCID 23499332, compound

Product 1

HCID 12727037HCID 12727037, compoundYield 91.3%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 4-[3-methoxybenzoyl]pyridine(790 mg, 3.7 mmol) and iodomethane (1.15 ml, 18.5 mmol) in acetone (10 mL) was stirred at room temperature for 48 h. The precipitate was filtered, washed with diethyl ether and dried in vacuo to give 1.2 g (91%) of an orange powder.

Workup

  1. filtrationThe precipitate was filtered
  2. washwashed with diethyl ether
  3. customdried in vacuo

Sources & evidence

ORD record
ord-7505b758e81548c987d0decc5c2067d6
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

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