Phosphorus pentachloride → HCID 23499367, compound

HRID 1836358Notes

Reaction equation

HRID 1836358 reaction equation
[I:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].P(Cl)(Cl)(Cl)(Cl)[Cl:13]>C(OCC)C>[I:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[C:4]([Cl:13])=[O:5]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 125201644-Fluoro-2-iodobenzoic acid

Product 1

HCID 23499367HCID 23499367, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 2-iodo-4-fluorobenzoic acid (194 mg, 0.73 mmol) and phosphorus pentachloride (152 mg, 0.73 mmol) in diethyl ether (5 mL) was stirred at room temperature for 2 h. The solvent was removed under reduced pressure to yield the 2-iodo-4-fluorobenzoyl chloride.

Workup

  1. customThe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-60de454f2d5041b087a7dee558c8d1f7
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

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