化工社化工社 化学情報印刷レポート · 研究参考用
Phosphorus pentachloride → 4-Fluoro-2-iodobenzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phosphorus pentachloride | HCID 24819 | — |
| 反応物 | 4-Fluoro-2-iodobenzoic acid | HCID 12520164 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 4-Fluoro-2-iodobenzoyl chloride | HCID 23499367 | — |
反応手順
A mixture of 2-iodo-4-fluorobenzoic acid (194 mg, 0.73 mmol) and phosphorus pentachloride (152 mg, 0.73 mmol) in diethyl ether (5 mL) was stirred at room temperature for 2 h. The solvent was removed under reduced pressure to yield the 2-iodo-4-fluorobenzoyl chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06777428B1 |
| 出典データセット | uspto-grants-2004_08 |
| ORD ID | ord-60de454f2d5041b087a7dee558c8d1f7 |
| 出典メモ | uspto-grants-2004_08 |