HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzaldehyde → 4-Trifluoromethyl-benzaldehyde o-methyloxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzaldehyde | HCID 67996 | — |
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Product | 4-Trifluoromethyl-benzaldehyde o-methyloxime | HCID 74057330 | 100% |
Reaction Steps
Reaction of 4-trifluoromethylbenzaldehyde with methoxylamine hydrochloride as described in the preparation of compound 3-A gave the title oxime ether as a clear oil (100% yield). 1HNMR indicated a 9:1 mixture of E- and Z-isomers. 1HNMR 400 MHz (CDCl3) δ (ppm): (E-isomer) 4.00 (3H, s, OCH3), 7.62 (2H, m, aromatics), 7.69 (2H, m, aromatics), 8.08 (1H, s, CH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777440B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-cab013eb2f3f437f98ffaf06c1a35bb6 |
| Source note | uspto-grants-2004_08 |