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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836534Generated: November 3, 2026

O-Methylhydroxylamine hydrochloride → HCID 74058497, compound

https://huagongshe.com/reaction/1836534

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-Methylhydroxylamine hydrochlorideHCID 521874—
ReactantTert-butyl 4-formylbenzoateHCID 2751588—
ProductHCID 74058497HCID 74058497—

Reaction Steps

Reaction of 4-formyl-benzoic acid tert-butyl ester with methoxylamine hydrochloride as described in the preparation of compound 3-A gave the title oxime ether as a clear oil after chromatography on silica gel ( elution hexane-ethyl acetate, 96:4) (79% yield). 1HNMR 400 MHz (CDCl3) δ (ppm): 1.60 (9H, s, t-Bu), 4.00 (3H, s, OCH3), 7.62 (2H, d, J=8.0 Hz, aromatics), 7.97 (2H, d, J=8.0 Hz, aromatics), 8.08 (1H, s, CH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777440B2
Source datasetuspto-grants-2004_08
ORD IDord-1063aaf635ef4dcd9ded6cdd93900365
Source noteuspto-grants-2004_08