Sodium ion → 2-[4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-butyrolactone

HRID 183677Notes

Reaction equation

HRID 183677 reaction equation
[Br:26][CH:27]1[C:28](=[O:29])[O:30][CH2:31][CH2:32]1.[H-:24].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1.[Na+:25].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:27]1[C:28](=[O:29])[O:30][CH2:31][CH2:32]1)[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 954632(3H)-Furanone, 3-bromodihydro-HCID 166653HydrideHCID 120422345-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

Product 1

HCID 227362412-[4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-butyrolactone

Sources & evidence

ORD record
ord-5bc3b0584796470e875797568668daec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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