HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylcyclohexylamine → n-Cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-n-methyl-2-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylcyclohexylamine | HCID 7514 | — |
| Reactant | 2-Methyl-5-nitrobenzoic acid | HCID 519683 | — |
| Reactant | n-Allyl-n-cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-2-fluorobenzamide | HCID 22180389 | — |
| Product | n-Cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-n-methyl-2-methylbenzamide | HCID 22180538 | — |
Reaction Steps
Steps (a) and (b) of Example 59 were repeated, except that 2-methyl-5-nitrobenzoic acid was used instead of 2-fluoro-5-nitrobenzoic acid. Step (c) of Example 59 was then repeated, except that N-methylcyclohexylamine was used instead of N-allylcyclohexylamine. Thus, the title compound was prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777414B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-27e5ab9e9c1e4c478c0472040644edfb |
| Source note | uspto-grants-2004_08 |