Water → HCID 9864311, compound

Participants

Reaction Steps

A mixture of 2-(methylsulfonyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidine (1 g, 2.629 mmol) and isobutylamine(0.52 ml) in NMP (10 ml) was stirred at ambient temperature for 18 h. Water (100 ml) was then added and the resulting precipitate was collected by filtration and dried (0.85 g). Trituration of this material with ether/cyclohexane gave the title compound as a colourless solid (0.62 g).

Provenance & Evidence