Benzocaine → HCID 806397, compound

HRID 1837147Notes

Reaction equation

HRID 1837147 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([OH:9])=O)([O-:3])=[O:2].[CH2:13]([O:15][C:16](=[O:24])C1C=CC(N)=CC=1)C.[CH:25]1C2C(=CC=CC=2)C=CC=1C(O)=O.I[C:39]1[CH:45]=[CH:44][C:42]([NH2:43])=[CH:41][CH:40]=1>>[CH3:13][O:15][C:16](=[O:24])[C:45]1[CH:39]=[CH:40][C:41]([CH3:25])=[C:42]([NH:43][C:7](=[O:9])[C:6]2[CH:10]=[CH:11][CH:12]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[CH:44]=1

Participants

5

Reactant 4

HCID 2337BenzocaineHCID 71232-Naphthoic acidHCID 84973-Nitrobenzoic acidHCID 108934-Iodoaniline

Product 1

HCID 806397HCID 806397, compound

Procedure

The title compound was synthesized by the same procedure as for Example 15 except 3-nitrobenzoic acid and ethyl-4-aminobenzoate were used instead of 2-napthoic acid and 4-iodoaniline. M+315.3, mp 208-209° C.

Sources & evidence

ORD record
ord-13aeff567ca64775a571c157d9cf3c58
Source dataset
uspto-grants-2004_08
Patent number
US06780883B2

Reaction notes

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