HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 23498112, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178496075 | HCID 178496075 | — |
| Product | HCID 23498112 | HCID 23498112 | 67% |
Reaction Steps
Following the procedure used to prepare Reference Example 12, reaction of 6-benzyloxy-4-hydroxy-7-(2-methoxyethoxy)-3-quinolinecarbonitrile with phosphorous oxychloride provides 6-benzyloxy-4-chloro-7-(2-methoxyethoxy)-3-quinolinecarbonitrile in 67% yield, mp 142-145° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06780996B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-8066f5cfe7e34389aa12f6473f66072a |
| Source note | uspto-grants-2004_08 |