HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenylethyl alcohol → 2-(3-nitrophenyl)acetaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenylethyl alcohol | HCID 104058 | — |
| Reactant | 1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide | HCID 339496 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(3-nitrophenyl)acetaldehyde | HCID 11528408 | — |
Reaction Steps
A mixture of 10 g of 2-(3-nitrophenyl)ethanol, 25.1 g of 1-hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide and 300 ml of tetrahydrofuran is heated at reflux for 6 hours. After filtration and concentration of the solvent, the product is used as it is in the following Step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06784183B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-d3e402bd917e4f69915b77f47a8198ff |
| Source note | uspto-grants-2004_08 |