p-Toluenesulfonic acid → HCID 69583690, compound

HRID 1837512Notes

Reaction equation

HRID 1837512 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH2:10][CH:11]([C:13]2[N:14]=[CH:15][N:16]([C:18]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:17]=2)O)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:13]2[N:14]=[CH:15][N:16]([C:18]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=3)[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:17]=2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 22186071HCID 22186071, compound

Product 1

HCID 69583690HCID 69583690, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 12.25 g of the product obtained in Step 2, 1 g of para-toluenesulphonic acid and 200 ml of toluene is heated at reflux for 5 hours. After returning to ambient temperature, washing the toluene solution with a 0.1N solution of sodium hydroxide and then with water, drying over magnesium sulphate and concentration, the expected product is obtained.

Workup

  1. temperatureis heated
  2. temperatureat reflux for 5 hours
  3. customAfter returning to ambient temperature
  4. washwashing the toluene solution with a 0.1N solution of sodium hydroxide
  5. dry with materialwith water, drying over magnesium sulphate and concentration

Sources & evidence

ORD record
ord-ac3c1f286b23410fb129b611fb547cbf
Source dataset
uspto-grants-2004_08
Patent number
US06784183B2

Reaction notes

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