HCID 10162481, compound → HCID 22677996, compound

HRID 1837538Notes

Reaction equation

HRID 1837538 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([C:12]2([CH2:19][CH2:20][CH2:21][C:22]#[C:23][C:24]3[CH:29]=[CH:28][CH:27]=[C:26]([N+:30]([O-])=O)[CH:25]=3)[S:16][C:15](=[O:17])[NH:14][C:13]2=[O:18])(=[O:11])=[O:10])=[CH:5][CH:4]=1>C(O)(=O)C.[Fe]>[NH2:30][C:26]1[CH:25]=[C:24]([C:23]#[C:22][CH2:21][CH2:20][CH2:19][C:12]2([S:9]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=3)(=[O:11])=[O:10])[S:16][C:15](=[O:17])[NH:14][C:13]2=[O:18])[CH:29]=[CH:28][CH:27]=1

Participants

4

Reactant 1

HCID 10162481HCID 10162481, compound

Product 1

HCID 22677996HCID 22677996, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Procedure

A sample of 5-(4-methoxybenzenesulfonyl)-5-[5-(3-nitrophenyl)pent-4-ynyl]-thiazolidine-2,4-dione of Example 118 was reduced with iron in acetic acid to give the title compound as crystals, m.p. 135-138° C.

Sources & evidence

ORD record
ord-d3f5fd477d764940af7bc96b1727200f
Source dataset
uspto-grants-2004_08
Patent number
US06784184B2

Reaction notes

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