Carbon tetrabromide → HCID 17837900, compound

HRID 1837694Notes

Reaction equation

HRID 1837694 reaction equation
[CH3:1][S:2]([C:5]1[C:10]2[O:11][CH2:12][O:13][C:9]=2[CH:8]=[CH:7][C:6]=1[CH2:14]O)(=[O:4])=[O:3].C(Br)(Br)(Br)[Br:17].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>ClCCl>[Br:17][CH2:14][C:6]1[CH:7]=[CH:8][C:9]2[O:13][CH2:12][O:11][C:10]=2[C:5]=1[S:2]([CH3:1])(=[O:4])=[O:3]

Participants

5

Reactant 3

HCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 22678512HCID 22678512, compound

Product 1

HCID 17837900HCID 17837900, compoundYield 95.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

907 mg of [2-(methylsulfonyl)-3,4-methylenedioxyphenyl]methanol, 1.31 g of carbon tetrabromide and 1.03 g of triphenylphosphine were dissolved in 5 ml of dichloromethane, and the mixture was stirred at room temperature for 30 minutes. The solvent was evaporated, and the residue was purified by silica gel column chromatography (ethyl acetate:hexane=1:3), to give 1.10 g of the title compound as a colorless oil.

Workup

  1. customThe solvent was evaporated
  2. customthe residue was purified by silica gel column chromatography (ethyl acetate:hexane=1:3)

Sources & evidence

ORD record
ord-e8ad4e151b9b436895e44a357c5d2514
Source dataset
uspto-grants-2004_08
Patent number
US06784192B2

Reaction notes

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