反应详情

温度

100 °C

2.2 g of (2-methoxy-3-pyridyl)methyl cyanide, 35 ml of a 1N aqueous sodium hydroxide and 35 ml of methanol were stirred under heating at 100° C. for 1.5 hours. The mixture was cooled to room temperature, and then, 35 ml of a 5N aqueous hydrochloric acid was added thereto, and the solvent was evaporated. Ethanol was added to the residue and a solid was filtered off. Ethanol was evaporated, and ethanol was added again to the residue and a solid was filtered off. Ethanol was evaporated, to give 2.4 g of white crystals.

1. temperatureThe mixture was cooled to room temperature
2. customthe solvent was evaporated
3. additionEthanol was added to the residue
4. filtrationa solid was filtered off
5. customEthanol was evaporated
6. additionethanol was added again to the residue
7. filtrationa solid was filtered off
8. customEthanol was evaporated