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HRID1837842

反应详情

EQUATION

反应方程式

HRID 1837842 的结构方程式

REACTANTS

反应物

3
结构：c1ccc(N2CCCC2)cc1
HCID77726

1-Phenylpyrrolidine

C10H13N

结构：COC(=O)C=CC=O
HCID111293

Methyl 4-oxo-2-butenoate

C5H6O3

结构：CN1C(=O)[C@H](Cc2ccccc2)N[C@@H]1C(C)(C)C
HCID10309834

(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone

C15H22N2O

PRODUCTS

生成物

1
结构：COC(=O)[C@H](CC=O)c1ccc(N2CCCC2)cc1
HCID86588398

未命名化合物

PROCEDURE

实验过程

This example describes a Friedel-Crafts alkylation reaction of 1-phenyl-pyrrolidine and 4-oxo-butenoic acid methyl ester, catalyzed by the hydrochloride salt of (1), to provide (R)-4-oxo-2-(4-pyrrolidin-1-yl-phenyl)-butyric acid methyl ester.