HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpyrrolidine → HCID 86588398, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpyrrolidine | HCID 77726 | — |
| Reactant | Methyl 4-oxobut-2-enoate | HCID 111293 | — |
| Reactant | 5-Benzyl-2-tert-butyl-3-methyl-4-imidazolidinone, (2S,5S)- | HCID 10309834 | — |
| Product | HCID 86588398 | HCID 86588398 | — |
Reaction Steps
This example describes a Friedel-Crafts alkylation reaction of 1-phenyl-pyrrolidine and 4-oxo-butenoic acid methyl ester, catalyzed by the hydrochloride salt of (1), to provide (R)-4-oxo-2-(4-pyrrolidin-1-yl-phenyl)-butyric acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06784323B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-c5d357304ae04caba5265fbaf7e33a6a |
| Source note | uspto-grants-2004_08 |