Bicarbonate Ion → [6-(3-Amino-propoxy)-7-methoxy-quinazolin-4-yl]-[3-chloro-4-(pyridin-2-ylmethoxy)-phenyl]-amine
Reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][CH2:15][CH2:16][CH2:17][O:18][c:19]1[cH:20][c:21]2[c:22]([NH:31][c:32]3[cH:33][c:34]([Cl:46])[c:35]([O:38][CH2:39][c:40]4[n:41][cH:42][cH:43][cH:44][cH:45]4)[cH:36][cH:37]3)[n:23][cH:24][n:25][c:26]2[cH:27][c:28]1[O:29][CH3:30])([CH3:12])([CH3:13])[CH3:47].[Cl:48][CH2:49][Cl:50].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[Na+:55].[O-:51][C:52]([OH:53])=[O:54]>>[NH2:14][CH2:15][CH2:16][CH2:17][O:18][c:19]1[cH:20][c:21]2[c:22]([NH:31][c:32]3[cH:33][c:34]([Cl:46])[c:35]([O:38][CH2:39][c:40]4[n:41][cH:42][cH:43][cH:44][cH:45]4)[cH:36][cH:37]3)[n:23][cH:24][n:25][c:26]2[cH:27][c:28]1[O:29][CH3:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7f8f62f5a8bc49538a3e4ca6d472d427
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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