HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanamine → HCID 18753280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanamine | HCID 31018 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 18753232 | HCID 18753232 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 18753280 | HCID 18753280 | — |
Reaction Steps
In analogy to the procedure described in example 38b, 4,6-dichloro-2-(2-hydroxy-ethyl-amino)-pyrimidine-5-carbonitrile was treated with 3-picolylamine in dioxane in the presence of N-ethyl-diisopropylamine at room temperature to yield 4-chloro-2-(2-hydroxy-ethylamino)-6-[(pyridin-3-ylmethyl)-amino]-pyrimidine-5-carbonitrile as a colorless foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673795B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-553c316fe393460e9481b54c0948b3d1 |
| Source note | uspto-grants-2004_01 |