HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 18753219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(4-Fluorophenyl)piperidine | HCID 2759136 | — |
| Reactant | HCID 18753299 | HCID 18753299 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18753219 | HCID 18753219 | — |
Reaction Steps
In analogy to the procedure described in example 75c, the 3-chloro-5-methyl-6-phenyl-pyrazine-2-carbonitrile was treated with 4-(4-fluoro-phenyl)-piperidine and N-ethyldiisopropylamine in N,N-dimethylformamide at room temperature to yield the 3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-5-methyl-6-phenyl-pyrazine-2-carbonitrile as yellow oil; MS: 373 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673795B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-cf3c2a37d0894f199a77e9cef21c60a1 |
| Source note | uspto-grants-2004_01 |