N-BOC-ethylenediamine → HCID 69034531, compound

Participants

Reaction Steps

In analogy to the procedure described in example 84c, 3-methylsulfanyl-5-(4-phenyl-piperazin-1-yl)-[1,2,4]triazine-6-carbonitrile was treated with N-Boc-ethylene-diamine in a sealed tube at 130° C. during 48 hours to yield {2-[6-cyano-5-(4-phenyl-piperazin-1-yl)-[1,2,4]triazin-3-ylamino]-ethyl}-carbamic acid tert-butyl ester as an amorphous, light yellow solid; MS: [M+H]+=425.

Provenance & Evidence