Fumaric Acid → L-Carnitine fumarate

Participants

Reaction Steps

To 10 mL of 95% v/v of ethanol at about 70° C., 2.28 g (0.01 moles) of acetyl L-carnitine inner salt (titre: 89.3%) and 1.16 g (0.01 moles) of fumaric acid were added under vigorous stirring. The resulting solution (“mother solution”) was cooled to room temperature while constantly keeping it under stirring. To the solution, a few milligrams of L-carnitine acid fumarate as precipitating agent were added. In few minutes a white, heavy precipitate formed which was filtered off one hour later.

Provenance & Evidence