Benzaldehyde → HCID 69893691, compound

HRID 1838649Notes

Reaction equation

HRID 1838649 reaction equation
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:9]([CH2:19][N+:20]#[C-:21])([C:12]1[CH:18]=[CH:17][C:15](C)=[CH:14][CH:13]=1)(=[O:11])=[O:10].[C-:22]#N.[Na+]>>[C:2]1([C@H:1]2[O:8][CH:21]=[N:20][C@@H:19]2[S:9]([C:12]2[C:13]([CH3:22])=[CH:14][CH:15]=[CH:17][CH:18]=2)(=[O:10])=[O:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 8929Sodium CyanideHCID 161915Tosylmethyl isocyanide

Product 1

HCID 69893691HCID 69893691, compound

Procedure

In a manner analogous to Preparation 1, benzaldehyde (0.41 mL, 4.03 mmol), tosylmethylisocyanide (0.75 g, 3.84 mmol) and NaCN (0.02 g, 0.40 mmol) gave the desired compound as a tan solid. MS(ES+) m/z 302.2 (M+H+).

Sources & evidence

ORD record
ord-fd5f7ad7323d471183df7c499f1f96e6
Source dataset
uspto-grants-2004_01
Patent number
US06673941B2

Reaction notes

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