Hydrochloric Acid → HCID 178429694, compound

Participants

Reaction Steps

2.7 kg of N-(4,5-bismethanesulfonyl-2-methylbenzoyl)guanidine are suspended in 25 l of ethanol at 60°, and 10.6 l of 1N HCl solution are added. On warming to 80°, a clear solution is obtained. The solution is allowed to cool slowly, with crystallisation beginning at 50°, The N-(4, 5-bismethanesulfonyl-2-methylbenzoyl)guanidine, hydrochloride obtained is subsequently dried to constant weight at 60°, giving N-(4,5-bismethanesulfonyl-2-methylbenzoyl)guanidine, hydrochloride.

Provenance & Evidence