HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → Methyl 4-(hydroxyiminomethyl)cinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Methyl 3-(4-formylphenyl)-2-propenoate | HCID 53401287 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | Methyl 4-(hydroxyiminomethyl)cinnamate | HCID 85782432 | — |
Reaction Steps
4.0 g of methyl 4-formylcinnamate are dissolved in 40 ml methanol and then 1.6 g hydroxylamine-hydrochloride and 1.9 g sodium acetate are added. The mixture is stirred overnight and then diluted with 300 ml water. The precipitate is filtered by suction, dried in vacuo and crystallized from ethyl acetate/petrolether. This gives 3.56 9 of the title compound. The mass spectrum shows the molecular peak MH+ at 206 Da.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673786B1 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-932790b0bcec480fab85395bee8075ec |
| Source note | uspto-grants-2004_01 |