反应详情

24.4 g of methyl 2-(4-formylphenoxy)acetate are dissolved in 300 ml methanol and then 9.6 g hydroxylamine hydrochloride and 11.33 g sodium acetate are added. The mixture is stirred overnight, then diluted with 1.2 l water and cooled. The precipitate is filtered off by suction, washed with cold water and dried under reduced pressure. This gives 18.43 g of the title compound. The mass spectrum shows the molecular peak MH+ at 210 Da.

1. temperaturecooled
2. filtrationThe precipitate is filtered off by suction
3. washwashed with cold water
4. customdried under reduced pressure