Benzenepropanoic acid → HCID 6957637, compound

HRID 1838930Notes

Reaction equation

HRID 1838930 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:30])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18](=[O:29])[CH:19](O)[CH2:20]CC2C=CC=CC=2)[CH2:14][CH2:13]1.[C:31]1(CCC(O)=O)[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1.OC1C=CC=CC=1[C@@H](CC)C(O)=O>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[NH:9][C:10](=[O:30])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18](=[O:29])[CH2:19][CH2:20][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH2:14][CH2:13]1

Participants

4

Reactant 3

HCID 107Benzenepropanoic acidHCID 12985297HCID 12985297, compoundHCID 69892093HCID 69892093, compound

Product 1

HCID 6957637HCID 6957637, compound

Procedure

Compound 12 was prepared in the manner of compound 7 substituting 3-phenylpropanoic acid for (R)-2-hydroxy-phenylbutyric acid in part C to afford compound 12: Mass spectrum (M+1)=380.40.

Sources & evidence

ORD record
ord-39e06467b7fd4b40a8755b5587812908
Source dataset
uspto-grants-2004_01
Patent number
US06677343B2

Reaction notes

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