Cyclohexanemethanol → HCID 5329590, compound

Participants

Reaction Steps

The mixture of 2-Amino-4-cyclohexylmethoxy-6-di(4-methoxybenzyl)amino-5-pyrimidine carbaldehyde and cyclohexylmethanol obtained previously was stirred in trifluoracetic acid (2 ml) at 65° C. for 24 h. The same workup procedure was used as previously, with purification of the product by column chromatography eluting with 40% EtOAc/petrol (40:60) yielding a pale yellow solid. M.p. 159-160° C.

Provenance & Evidence