Tert-Butylamine → HCID 69827556, compound

Participants

Reaction Steps

(2R,3 R,4R,5S)-4-(acetyloxy)-5-(3-bromoisoxazol-5-yl)-2-[6-(4-chloro-2-fluoroanilino)-9H-purin-9-yl]tetrahydrofuran-3-yl acetate (16.8 mg) was treated with t-butylamine (0.08 ml) in methanol (0.8 ml) at 0° C. for 1.5 h, and the mixture was evaporated to dryness to give the title compound (16 mg).

Provenance & Evidence