HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 23449059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester | HCID 17453 | — |
| Reactant | Imidazo(4,3-b)(1,3)thiazole-7-carbaldehyde | HCID 22390357 | — |
| Product | HCID 23449059 | HCID 23449059 | — |
Reaction Steps
7-Formyl-imidazo[5,1-b]thiazole was dissolved in 15 ml of methanol. Methyl (triphenylphosphoranylidene)acetate (500 mg) was added to the solution. The mixture was stirred at room temperature for 15 min. The reaction solution was concentrated under the reduced pressure. The concentrate was purified by chromatography on silica gel to give 208 mg of 7-((E)-3-Oxo-1-buten-1-yl)imidazo[5,1-b]thiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06677331B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-3dea4994371740419aa96727e987f950 |
| Source note | uspto-grants-2004_01 |