4-methoxy-N-(2-nitrophenyl)benzamide → N-(2-Aminophenyl)-4-methoxybenzamide

HRID 1839457Notes

Reaction equation

HRID 1839457 reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][C:6]([C:7]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N+:16]([O-])=O)=[O:8])=[CH:5][CH:4]=1>C(OCC)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:9][C:10]2[C:11]([NH2:16])=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:8])=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 3460424-methoxy-N-(2-nitrophenyl)benzamide

Product 1

HCID 785232N-(2-Aminophenyl)-4-methoxybenzamide

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Using a procedure similar to Example 1C except starting with N-(4-methoxybenzoyl)-2-nitroaniline in ethyl acetate, the title compound was obtained as a white solid (99%); MS(FD): 242.

Sources & evidence

ORD record
ord-b0b74ea0f0424fb892d565d42f9c454b
Source dataset
uspto-grants-2004_01
Patent number
US06677369B2

Reaction notes

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