Tetrahydrofuran → 2,2-dimethyl-1-(2-methyl-1-trityl-1H-imidazol-4-yl)propan-1-ol
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Li:5].[CH3:6][c:7]1[n:8]([C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:9][c:10]([CH:12]=[O:13])[n:11]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[CH:12]([c:10]1[cH:9][n:8]([C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:7]([CH3:6])[n:11]1)[OH:13]Participants
4
Sources & evidence
- ORD record
- ord-f1309685ee5e48778514a516bb239c9f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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