(Chloromethyl)cyclopropane → HCID 23447717, compound

HRID 1840274Notes

Reaction equation

HRID 1840274 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:5][CH:4]=1.Cl[CH2:30][CH:31]1[CH2:33][CH2:32]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:30][CH:31]3[CH2:33][CH2:32]3)[C:11](=[O:23])[C:10]=2[C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 80013(Chloromethyl)cyclopropaneHCID 12568067HCID 12568067, compound

Product 1

HCID 23447717HCID 23447717, compoundYield 89.1%

Procedure

Using 5,6-bis(4-methoxyphenyl)-4-ethoxycarbonyl-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 19 were repeated likewise, whereby the title compound was obtained in a yield of 89.1%.

Sources & evidence

ORD record
ord-34c961216ece4e0aafa8fe9c08a267e2
Source dataset
uspto-grants-2004_01
Patent number
US06680316B1

Reaction notes

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