Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840298Generated: November 2, 2026

Methyl 3-phenyl-4-isoxazolecarboxylate → 3-Phenyl-1,2-oxazole-4-carboxylic acid

https://huagongshe.com/reaction/1840298

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-phenyl-4-isoxazolecarboxylateHCID 10750662—
Reactant3-(4-Fluoro-phenyl)-isoxazole-4-carboxylic acidHCID 23447885—
Product3-Phenyl-1,2-oxazole-4-carboxylic acidHCID 13152278—

Reaction Steps

This compound was synthesised following the procedure described for Compound 8D but using Compound 15A instead of Compound 8C (90.2%). M.p. 162.7-164.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06680319B2
Source datasetuspto-grants-2004_01
ORD IDord-55bb8b2ab8ef49fcb4e0b3a5185a6bdd
Source noteuspto-grants-2004_01