HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)phenyl isothiocyanate → HCID 23447744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)phenyl isothiocyanate | HCID 737162 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | N,N-Dimethyl-3-amino-6-chloro-2-hydroxybenzenesulfonamide | HCID 23447758 | — |
| Product | HCID 23447744 | HCID 23447744 | 52% |
Reaction Steps
Following the general procedure for thiourea formation outlined in example 12, N,N-dimethyl-3-amino-6-chloro-2-hydroxybenzenesulfonamide (500 mg, 2 mmol) and 2-trifluoromethylphenylisothiocyanate (548 mg, 2 mmol) were coupled to form the desired thiourea (469 mg, 52%). EI-MS m/z 454.0 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680317B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-5e379e2fcd7d4d909e4db8a95733c303 |
| Source note | uspto-grants-2004_01 |