HCID 23448162, compound → HCID 69820511, compound

Participants

Reaction Steps

The process is performed in the same way as in Example 1.6, and, starting with 1.11 g (3.0 mmol) of 2-[bis(1-oxopropyl)amino]-3-cyclopentylbenzenesulphonyl chloride and 1.21 g (3.0 mmol) of (S)-1-[2-amino-5-(5-amino-2-pyrazinyl)-1-oxopentyl]-4-(difluoromethylene)piperidine hydrochloride (2:1), 1.3 g of (S)-N-[2-[[[4-(5-amino-2-pyrazinyl)-1-[[4-(difluoromethylene)piperid-1-yl]carbonyl]butyl]amino]sulphonyl]-6-cyclopentylphenyl]propanamide are obtained.

Provenance & Evidence