HCID 9904377, compound → HCID 20612659, compound

HRID 1840664Notes

Reaction equation

HRID 1840664 reaction equation
[CH:1]1([NH:7][C:8](=[O:22])/[CH:9]=[CH:10]/[CH:11]=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]3[O:19][CH2:20][O:21][C:15]=3[CH:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>[Pd].C(OC(=O)C)C>[CH:1]1([NH:7][C:8](=[O:22])[CH2:9][CH2:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]3[O:19][CH2:20][O:21][C:15]=3[CH:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 9904377HCID 9904377, compound

Product 1

HCID 20612659HCID 20612659, compoundYield 84%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To 5-(3,4-methylenedioxy phenyl)-2E,4E-pentadienoic acid cyclohexyl amide (300 mg) was added 5% Pd/C (30 mg) and hydrogenated the contents at 30 psi for 1 hr. The solution was filtered and rotary evaporated to yield a white solid. Recrystallisation from ethylacetate and petroleum spirit yielded pure white crystals (255 mg, yield 84%). m.p. 145.4° C.-146.3° C.

Workup

  1. customfor 1 hr
  2. filtrationThe solution was filtered
  3. customrotary evaporated
  4. customto yield a white solid

Sources & evidence

ORD record
ord-72961af0f9db49a09d92aec1056aee26
Source dataset
uspto-grants-2004_01
Patent number
US06680391B2

Reaction notes

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