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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840875Generated: November 1, 2026

1-Iodooctane → 6-Acetyl-4,4-dimethyl-1-octyl-3,4-dihydroquinolin-2(1H)-one

https://huagongshe.com/reaction/1840875

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IodooctaneHCID 12380—
Reactant2(1H)-Quinolinone, 6-acetyl-1-hexyl-3,4-dihydro-4,4-dimethyl-HCID 12135416—
Product6-Acetyl-4,4-dimethyl-1-octyl-3,4-dihydroquinolin-2(1H)-oneHCID 23444704—

Reaction Steps

Following a procedure similar to that used for the preparation of Intermediate 6a but using 1-iodo-n-octane as the alkylating reagent the title compound was obtained as a colorless oil (86% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683092B1
Source datasetuspto-grants-2004_01
ORD IDord-ba6dfb286217485bbdf9cb62cd0fe085
Source noteuspto-grants-2004_01