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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840893Generated: October 30, 2026

cis-Cinnamic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(Z-3-phenylpropenamide)

https://huagongshe.com/reaction/1840893

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-Cinnamic acidHCID 5372954—
Reactant(R)-(+)-3-Aminoquinuclidine DihydrochlorideHCID 12494972—
Product(R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(Z-3-phenylpropenamide)HCID 69684672—

Reaction Steps

Prepared as a free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride, and Z-3-phenylpropenoic acid; MS (ES+) 257 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683090B1
Source datasetuspto-grants-2004_01
ORD IDord-36b1dbe1cb6f47d1acfc207fb775df99
Source noteuspto-grants-2004_01