HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoroindole → 5-fluoro-3-(piperidin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoroindole | HCID 67861 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 5-fluoro-3-(piperidin-4-yl)-1H-indole | HCID 11769929 | — |
Reaction Steps
This compound was prepared following the procedure described in Example 1 (parts A and B) starting with 0.7 g (5.5 mmol) of 5-fluoroindol and 2.1 g (13.6 mmol) of 4-piperidone monohydrate hydrochloride. After the usual work-up 0.8 g (67% of yield) of the desired product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683096B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-fe0eeb1995d145d5a9e718020c68c484 |
| Source note | uspto-grants-2004_01 |