1-Bromo-2-Chloroethane → Methyl 2-(2-chloroethoxy)-4-methoxybenzoate

Participants

Reaction Steps

This compound was prepared following the procedure described in Example 1 (part C) starting with 5 g (27.4 mmol) of 2-hydroxy-5-methyl-benzoic acid methyl ester, 9 mL (60.3 mmol) of 1-bromo-2-chloro-ethane and 5.9 g (42.8 mmol) of potassium carbonate. After the work-up and purification, 6.6 g (99% of yield) of the desired product was obtained.

Provenance & Evidence